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Comment
. 2016 Nov 17;167(5):1159-1160.
doi: 10.1016/j.cell.2016.11.011.

A New Path through the Nuclear Pore

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Comment

A New Path through the Nuclear Pore

Alejandro Gozalo et al. Cell. .
Free article

Abstract

Knowing the configuration of the nuclear pore is essential for appreciating the underlying mechanisms of nucleo-cytoplasmic communication. Now, Fernandez-Martinez et al. present a high-resolution structure of the cytoplasmic nuclear pore-mRNA export holo-complex, challenging our textbook depiction of this massive membrane-embedded complex.

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  • Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform.
    Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, Sali A, Rout MP. Fernandez-Martinez J, et al. Cell. 2016 Nov 17;167(5):1215-1228.e25. doi: 10.1016/j.cell.2016.10.028. Epub 2016 Nov 10. Cell. 2016. PMID: 27839866 Free PMC article.

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