Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Jun;44(6):890-3.

Human pregnancy-specific beta 1-glycoproteins are coded within chromosome 19

T R Barnett  1 , W Pickle 2nd, P M Rae, J Hart, M Kamarck, J Elting
Affiliations

Human pregnancy-specific beta 1-glycoproteins are coded within chromosome 19

T R Barnett et al. Am J Hum Genet. 1989 Jun.

Abstract

We have isolated and characterized cDNAs that code for apoproteins having amino acid sequences highly similar to pregnancy-specific beta 1-glycoproteins (PS beta G). cDNAs coding for PS beta Gs, as well as the cDNA clone reported here, are members of the carcinoembryonic antigen (CEA) gene family. The previous localization of CEA-related genes to human chromosome 19, and the high level of DNA sequence conservation in the CEA family, suggested that the PS beta G genes are also located on this chromosome. We demonstrate here that chromosome 19 is indeed the site of PS beta G sequences. Our finding is in contrast to the recently reported indication that pregnancy-specific glycoproteins are encoded in chromosomes X and 6.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1983 Jul;80(14):4460-3 - PubMed
    1. Anal Biochem. 1984 Feb;137(1):266-7 - PubMed
    1. Eur J Immunol. 1985 Jan;15(1):103-6 - PubMed
    1. Crit Rev Oncol Hematol. 1985;2(4):355-99 - PubMed
    1. Proc Natl Acad Sci U S A. 1987 Feb;84(4):920-4 - PubMed

Substances

LinkOut - more resources