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Review
. 2016 Dec;40(8):549-555.
doi: 10.1053/j.semperi.2016.09.007. Epub 2016 Nov 15.

Outcomes in childhood following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE)

Girija Natarajan  1 , Athina Pappas  1 , Seetha Shankaran  2
Affiliations
Review

Outcomes in childhood following therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (HIE)

Girija Natarajan et al. Semin Perinatol. 2016 Dec.

Abstract

In this article, we review the childhood outcomes of neonates with birth depression and/or hypoxic-ischemic encephalopathy. The outcomes of these children prior to the era of hypothermia for neuroprotection will first be summarized, followed by discussion of results from randomized controlled trials of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy. The predictors of outcome in childhood following neonatal HIE using clinical and imaging biomarkers following hypothermia therapy will be described.

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References

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