Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jun 1;46(3):797-797n.
doi: 10.1093/ije/dyw211.

Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord

Geneviève Chêne  1   2   3 , Andrew Phillips  4 , Dominique Costagliola  5 , Jonathan A C Sterne  6 , Hansjakob Furrer  7 , Julia Del Amo  8   9 , Amanda Mocroft  4 , Antonella d'Arminio Monforte  10 , François Dabis  1   2   3 , José M Miro  11 , Diana Barger  1   2 , Monique Termote  1   2 , Christine Schwimmer  1   2 , Rikke Salbøl Brandt  12 , Nina Friis-Moller  12   13 , Dorthe Raben  12 , David Haerry  14 , Matthias Egger  15   16 , Ian Weller  4 , Stéphane De Wit  17
Affiliations
Free PMC article

Cohort Profile: Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCoord

Geneviève Chêne et al. Int J Epidemiol. .
Free PMC article

Abstract

Many questions about the long-term effects of combination antiretroviral therapy (cART) on clinical outcomes in people living with HIV (PLWH) and their impact on health systems remain unanswered. The Collaboration of Observational HIV Epidemiological Research Europe (COHERE) was formed in 2005 to pool and harmonize existing longitudinal data on people living with HIV in Europe, to answer key research questions that could not be addressed adequately by individual cohorts. Key research questions include long-term prognosis, rare outcomes, and variations across patient groups, settings and health systems. COHERE uses the HIV Cohorts Data Exchange Protocol, a standardized and validated method of data structure and transfer, to compile data from over 40 cohorts of PLWH residing in Europe, representing 331 481 individuals, including 2808 children (<13), representing 2 135 896 person-years of follow-up. COHERE compiles data on clinical characteristics, antiretroviral therapy and other medications, HIV seroconversion, opportunistic infections, laboratory results and socio demographic data. External collaborators interested in conducting a project in COHERE should submit a project proposal to the Regional Coordinating Centres in Bordeaux and Copenhagen for review by COHERE’s governing bodies (see www.cohere.org for further information).

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

DC was a member of the French Gilead HIV board up until 2015 and gave lectures for Janssen-Cilag, Merck-Sharp & Dohme-Chibret, ViiV and received travel/accommodations/meeting expenses from Gilead, ViiV, Janssen-Cilag. DC also conducted post-marketing studies for Janssen-Cilag, Merck-Sharp & Dohme-Chibret and ViiV. DC is currently a consultant at Innavirvax. HF has received grants from the Swiss National Science Foundation. His institution has received grants from ViiV, Abbvie, MSD, Janssen, Roche, BMS, and Gilead. The other co-authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
See this image and copyright information in PMC

References

    1. Mocroft A, Ledergerber B, Katlama C, et al. Decline in the AIDS and death rates in the EuroSIDA study: an observational study. The Lancet. 2003;362:22–9. - PubMed
    1. EuroCoord: Enhancing clinical and epidemiological HIV research in Europe through cohort collaborations. 2014. [cited 2014 5 February]; Available from: http://www.eurocoord.net/
    1. May MT, Ingle SM, Costagliola D, et al. Cohort profile: Antiretroviral Therapy Cohort Collaboration (ART-CC) Int J Epidemiol. 2013 - PMC - PubMed
    1. Egger M, Ekouevi DK, Williams C, et al. Cohort Profile: the international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa. Int J Epidemiol. 2012;41:1256–64. - PMC - PubMed
    1. EuroSida. 2015. [cited 6 July, 2015]; Available from: http://www.cphiv.dk/Ongoing-Studies/EuroSIDA/About.

Publication types

Substances