Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2016 Oct;8(10):E1321-E1327.
doi: 10.21037/jtd.2016.10.81.

Bleeding in continuous flow left ventricular assist device recipients: an acquired vasculopathy?

Snehal R Patel  1 , Sasa Vukelic  1 , Ulrich P Jorde  1
Affiliations
Editorial

Bleeding in continuous flow left ventricular assist device recipients: an acquired vasculopathy?

Snehal R Patel et al. J Thorac Dis. 2016 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Proposed pathways of development of arteriovenous malformations (AVM) during continuous flow left ventricular assist devices (CF LVAD) support.
See this image and copyright information in PMC

Comment on

References

    1. Uriel N, Pak SW, Jorde UP, et al. Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 2010;56:1207-13. 10.1016/j.jacc.2010.05.016 - DOI - PubMed
    1. Tsai HM, Sussman II, Nagel RL. Shear stress enhances the proteolysis of von Willebrand factor in normal plasma. Blood 1994;83:2171-9. - PubMed
    1. Geisen U, Heilmann C, Beyersdorf F, et al. Non-surgical bleeding in patients with ventricular assist devices could be explained by acquired von Willebrand disease. Eur J Cardiothorac Surg 2008;33:679-84. 10.1016/j.ejcts.2007.12.047 - DOI - PubMed
    1. Meyer AL, Malehsa D, Budde U, et al. Acquired von Willebrand syndrome in patients with a centrifugal or axial continuous flow left ventricular assist device. JACC Heart Fail 2014;2:141-5. 10.1016/j.jchf.2013.10.008 - DOI - PubMed
    1. Netuka I, Kvasnička T, Kvasnička J, et al. Evaluation of von Willebrand factor with a fully magnetically levitated centrifugal continuous-flow left ventricular assist device in advanced heart failure. J Heart Lung Transplant 2016;35:860-7. 10.1016/j.healun.2016.05.019 - DOI - PubMed

LinkOut - more resources