Th2/Th17 reciprocal regulation: twists and turns in the complexity of asthma phenotypes

Affiliations

¹ Laboratory for Respiratory Mucosal Immunity, School of Biomedical Sciences, The University of Queensland, Queensland 4072, Australia.
² QIMR Berghofer Medical Research Institute, Queensland 4029, Australia.
³ Laboratory for Respiratory Mucosal Immunity, School of Biomedical Sciences, The University of Queensland, Queensland 4072, Australia;; Australian Infectious Diseases Research Centre, The University of Queensland, Queensland 4072, Australia.

Comment

Jason P Lynch et al. Ann Transl Med. 2016 Oct.

. 2016 Oct;4(Suppl 1):S59.

doi: 10.21037/atm.2016.10.69.

¹ Laboratory for Respiratory Mucosal Immunity, School of Biomedical Sciences, The University of Queensland, Queensland 4072, Australia.
² QIMR Berghofer Medical Research Institute, Queensland 4029, Australia.
³ Laboratory for Respiratory Mucosal Immunity, School of Biomedical Sciences, The University of Queensland, Queensland 4072, Australia;; Australian Infectious Diseases Research Centre, The University of Queensland, Queensland 4072, Australia.

No abstract available

Conflict of interest statement

Simon Phipps has received grants from Pfizer and GSK. The other authors have no conflicts of interest to declare.

TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.
Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, Siddiqui S, Jia G, Ohri CM, Doran E, Vannella KM, Butler CA, Hargadon B, Sciurba JC, Gieseck RL, Thompson RW, White S, Abbas AR, Jackman J, Wu LC, Egen JG, Heaney LG, Ramalingam TR, Arron JR, Wynn TA, Bradding P. Choy DF, et al. Sci Transl Med. 2015 Aug 19;7(301):301ra129. doi: 10.1126/scitranslmed.aab3142. Sci Transl Med. 2015. PMID: 26290411

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