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Comment
. 2016 Oct;4(Suppl 1):S62.
doi: 10.21037/atm.2016.10.64.

Epidermal growth factor as a prognostic biomarker in chronic kidney diseases

Yoshitaka Isaka  1
Affiliations
Comment

Epidermal growth factor as a prognostic biomarker in chronic kidney diseases

Yoshitaka Isaka. Ann Transl Med. 2016 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
EGF and EGFR axis. Intrarenal EGF expression is decreased due to tubular injury, and decreased urine EGF excretion is a better biomarker for CKD progression. Although EGFR activation promotes cell proliferation and regeneration, activated EGFR may induce interstitial fibrosis or hypertension. EGF, epidermal growth factor; EGFR, EGF receptor; CKD, chronic kidney disease.
See this image and copyright information in PMC

Comment on

  • Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker.
    Ju W, Nair V, Smith S, Zhu L, Shedden K, Song PXK, Mariani LH, Eichinger FH, Berthier CC, Randolph A, Lai JY, Zhou Y, Hawkins JJ, Bitzer M, Sampson MG, Thier M, Solier C, Duran-Pacheco GC, Duchateau-Nguyen G, Essioux L, Schott B, Formentini I, Magnone MC, Bobadilla M, Cohen CD, Bagnasco SM, Barisoni L, Lv J, Zhang H, Wang HY, Brosius FC, Gadegbeku CA, Kretzler M; ERCB, C-PROBE, NEPTUNE, and PKU-IgAN Consortium. Ju W, et al. Sci Transl Med. 2015 Dec 2;7(316):316ra193. doi: 10.1126/scitranslmed.aac7071. Sci Transl Med. 2015. PMID: 26631632 Free PMC article.

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