Enterocyte progenitors can dedifferentiate to replace lost Lgr5⁺ intestinal stem cells revealing that many different progenitor populations can regain stemness

Affiliations

¹ Cell Biology, Stem Cell and Development Graduate Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
² Cell Biology, Stem Cell and Development Graduate Program, University of Colorado School of Medicine, Aurora, CO 80045, USA; Division of Gastroenterology, Hepatology and Nutrition, Dept. of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.

Editorial

Jennifer C Jones et al. Stem Cell Investig. 2016.

. 2016 Oct 21:3:61.

doi: 10.21037/sci.2016.09.15. eCollection 2016.

¹ Cell Biology, Stem Cell and Development Graduate Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
² Cell Biology, Stem Cell and Development Graduate Program, University of Colorado School of Medicine, Aurora, CO 80045, USA; Division of Gastroenterology, Hepatology and Nutrition, Dept. of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.

No abstract available

Conflict of interest statement

The authors have no conflicts of interest to declare.

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.
Tetteh PW, Basak O, Farin HF, Wiebrands K, Kretzschmar K, Begthel H, van den Born M, Korving J, de Sauvage F, van Es JH, van Oudenaarden A, Clevers H. Tetteh PW, et al. Cell Stem Cell. 2016 Feb 4;18(2):203-13. doi: 10.1016/j.stem.2016.01.001. Epub 2016 Jan 28. Cell Stem Cell. 2016. PMID: 26831517

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