[Humoral and cellular immunity in patients with left- and right-sided intracerebral tumors]

Abstract

The authors compared the values of the immune status of patients with glial brain tumor of grade III-IV anaplasia in the left and right side in the preoperative period. In patients with the tumor in the right hemisphere, in the frontotemporal region in particular, the absolute number of rosette-forming cells in peripheral blood and the blast-transformation activity of lymphocytes in response to phytohemagglutinin were reduced significantly (p less than 0.05) as compared to the values in patients with the tumor on the left side. The number of B-lymphocytes and the blood immunoglobulin level were not changed. The possible mechanisms of the revealed differences are discussed with due account of data on immunogenesis regulation by the left hemisphere.