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Published Erratum
. 2016 Nov 22;8(1):123.
doi: 10.1186/s13073-016-0377-x.

Erratum to: Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens

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Published Erratum

Erratum to: Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens

Thuy Doan et al. Genome Med. .
No abstract available

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Figures

Fig. 3
Fig. 3
Identification of rubella virus (RV) by metagenomic deep sequencing (MDS). a Illustrates how the 9688 nucleotide paired-end sequence reads obtained from sequencing the RNA extracted from subject 6’s aqueous fluid aligned to the most closely matched RV genome (GenBank DQ388280.1): 99.3% of the total RV genome is represented. Positions of synonymous (black vertical lines) and non-synonymous (red vertical lines) variants are shown. Of the 149 substitutions, 107 were synonymous and 42 were non-synonymous. Of the 42 non-synonymous mutations, 25 occurred within the coding region for the E1 and E2 glycoproteins. Per unit length, the number of non-synonymous mutations in the E1 and E2 proteins was 6.3-fold higher than in the non-structural proteins. The cyan marker above the E1 gene represents the 739-nucleotide sequence window recommended by the World Health Organization (WHO) for RV genotyping. b Phylogenetic analysis of subject 6’s RV strain obtained from MDS with 32 WHO reference strains, GUZ_GER92 (Stuttgart strain), and the RV27/3 vaccine strain, demonstrating that the subject’s RV sequence was most closely related to the genotype 1G viruses and not the vaccine strain

Erratum for

References

    1. Doan T, Wilson MR, Crawford ED, Chow ED, Khan LM, Knopp KA, O’Donovan BD, Xia D, Hacker JK, Stewart JM, Gonzales JA, Archarya NR, DeRisi JL. Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens. Genome Med. 2016;8:106. doi: 10.1186/s13073-016-0360-6. - DOI - PMC - PubMed

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