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Review
. 2017 Jan;58(1):23-28.
doi: 10.2967/jnumed.116.183152. Epub 2016 Nov 22.

Metabolic Imaging in Parkinson Disease

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Free article
Review

Metabolic Imaging in Parkinson Disease

Sanne K Meles et al. J Nucl Med. 2017 Jan.
Free article

Abstract

This review focuses on recent human 18F-FDG PET studies in Parkinson disease. First, an overview is given of the current analytic approaches to metabolic brain imaging data. Next, we discuss how 18F-FDG PET studies have advanced understanding of the relation between distinct brain regions and associated symptoms in Parkinson disease, including cognitive decline. In addition, the value of 18F-FDG PET studies in differential diagnosis, identifying prodromal patients, and the evaluation of treatment effects are reviewed. Finally, anticipated developments in the field are addressed.

Keywords: FDG-PET; Parkinson’s disease; imaging; metabolism; networks.

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