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. 2017 Feb;29(5).
doi: 10.1002/adma.201603864. Epub 2016 Nov 24.

Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

Wansong Chen  1   2 , Jiang Ouyang  2 , Hong Liu  3 , Min Chen  2 , Ke Zeng  2 , Jianping Sheng  2 , Zhenjun Liu  2 , Yajing Han  2 , Liqiang Wang  2 , Juan Li  2 , Liu Deng  2 , You-Nian Liu  1   2 , Shaojun Guo  4   5
Affiliations

Black Phosphorus Nanosheet-Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer

Wansong Chen et al. Adv Mater. 2017 Feb.

Abstract

A black phosphorus (BP)-based drug delivery system for synergistic photodynamic/photothermal/chemotherapy of cancer is constructed. As a 2D nanosheet, BP shows super high drug loading capacity and pH-/photoresponsive drug release. The intrinsic photothermal and photodynamic effects of BP enhance the antitumor activities. The synergistic photodynamic/photothermal/chemotherapy makes BP-based drug delivery system a multifunctional nanomedicine platform.

Keywords: black phosphorus nanosheets; chemotherapy; photodynamic therapy; photothermal therapy; synergistic therapy, drug delivery.

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