Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jun;6(1):133-140.
doi: 10.1007/s40123-016-0073-3. Epub 2016 Nov 24.

The Impact of Non-Steroidal Anti-Inflammatory Agents after Phacoemulsification on Quality of Life: A Randomized Study

Irini P Chatziralli  1 , Theodoros N Sergentanis  2 , Efstratios A Parikakis  3 , Leonidas E Papazisis  4 , Panagiotis Mitropoulos  3 , Marilita M Moschos  5
Affiliations

The Impact of Non-Steroidal Anti-Inflammatory Agents after Phacoemulsification on Quality of Life: A Randomized Study

Irini P Chatziralli et al. Ophthalmol Ther. 2017 Jun.

Abstract

Introduction: The purpose of our study was to investigate the impact of ketorolac addition to the well-established combination of antibiotic-steroid agent in terms of vision-related quality of life.

Methods: Patients were randomized to: (1) fixed combination of tobramycin 0.3%-dexamethasone 0.1%, one drop qid (n = 68) and (2) fixed combination of tobramycin 0.3%-dexamethasone 0.1%, one drop qid, plus ketorolac tromethamine 0.5%, one drop tid (n = 70). All patients completed the VFQ-25 questionnaire to assess their functional vision before cataract surgery and postoperatively on days 7, 28 and 42. The statistical analysis comprised the point-wise comparison between the two groups at the four time points for all sub-scales of the VFQ-25 questionnaire, as well as the composite score.

Results: No significant differences were noted regarding the composite score, as well as all subscales in all examined time points.

Conclusions: The addition of ketorolac did not seem to offer any additional benefit in terms of vision-related quality of life.

Keywords: Cataract; Function; Quality of life; VFQ-25.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flowchart, showing the study design and randomization
Fig. 2
Fig. 2
VFQ-25 composite score values (mean ± SD) in the two study groups
See this image and copyright information in PMC

References

    1. Eye Diseases Prevalence Research Group Causes and prevalence of visual impairment among adults in the United States. Arch Ophthalmol. 2004;122:477–485. doi: 10.1001/archopht.122.4.477. - DOI - PubMed
    1. Greenberg PB, Tseng VL, Wu WC, Liu J, Jiang L, Chen CK, Scott IU. Friedmann. Prevalence and predictors of ocular complications associated with cataract surgery in United States veterans. Ophthalmology. 2011;118:507–514. doi: 10.1016/j.ophtha.2010.07.023. - DOI - PubMed
    1. Bilbao A, Quintana JM, Escobar A, García S, Andradas E, Baré M. Elizalde B; IRYSS-Cataract Group. Responsiveness and clinically important differences for the VF-14 index, SF-36, and visual acuity in patients undergoing cataract surgery. Ophthalmology. 2009;116:418–424. doi: 10.1016/j.ophtha.2008.11.020. - DOI - PubMed
    1. Rosen PN, Kaplan RM, David K. Measuring outcomes of cataract surgery using the quality of Well-Being Scale and VF-14 Visual Function Index. J Cataract Refract Surg. 2005;31:369–378. doi: 10.1016/j.jcrs.2004.04.043. - DOI - PubMed
    1. Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Hays RD, Berry S. National Eye Institute Visual Function Questionnaire Field Test Investigators. Development of the 25-item National Eye Institute visual function questionnaire. Arch Ophthalmol. 2001;119:1050–1058. doi: 10.1001/archopht.119.7.1050. - DOI - PubMed

LinkOut - more resources