Ensuring Patient-Centered Access to Cardiovascular Disease Medicines in Low-Income and Middle-Income Countries Through Health-System Strengthening

Dan N Tran¹, Benson Njuguna², Timothy Mercer³, Imran Manji², Lydia Fischer³, Marya Lieberman⁴, Sonak D Pastakia⁵

Affiliations

¹ Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA.
² Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA; Department of Pharmacy, Moi Teaching and Referral Hospital, PO Box 3, Eldoret 30100, Kenya.
³ Department of Medicine, Indiana University School of Medicine, 1120 West Michigan Street, Indianapolis, IN 46202, USA.
⁴ Department of Chemistry and Biochemistry, University of Notre Dame, 250 Nieuwland, Notre Dame, IN 46556, USA.
⁵ Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA. Electronic address: spastaki@gmail.com.

PMID: 27886782
PMCID: PMC9771684
DOI: 10.1016/j.ccl.2016.08.008

Review

Ensuring Patient-Centered Access to Cardiovascular Disease Medicines in Low-Income and Middle-Income Countries Through Health-System Strengthening

Dan N Tran et al. Cardiol Clin. 2017 Feb.

. 2017 Feb;35(1):125-134.

doi: 10.1016/j.ccl.2016.08.008.

Authors

Dan N Tran¹, Benson Njuguna², Timothy Mercer³, Imran Manji², Lydia Fischer³, Marya Lieberman⁴, Sonak D Pastakia⁵

Affiliations

¹ Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA.
² Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA; Department of Pharmacy, Moi Teaching and Referral Hospital, PO Box 3, Eldoret 30100, Kenya.
³ Department of Medicine, Indiana University School of Medicine, 1120 West Michigan Street, Indianapolis, IN 46202, USA.
⁴ Department of Chemistry and Biochemistry, University of Notre Dame, 250 Nieuwland, Notre Dame, IN 46556, USA.
⁵ Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA. Electronic address: spastaki@gmail.com.

PMID: 27886782
PMCID: PMC9771684
DOI: 10.1016/j.ccl.2016.08.008

Abstract

Cardiovascular disease (CVD) is the leading cause of global mortality and is expected to reach 23 million deaths by 2030. Eighty percent of CVD deaths occur in low-income and middle-income countries (LMICs). Although CVD prevention and treatment guidelines are available, translating these into practice is hampered in LMICs by inadequate health care systems that limit access to lifesaving medications. In this review article, we describe the deficiencies in the current LMIC supply chains that limit access to effective CVD medicines, and discuss existing solutions that are translatable to similar settings so as to address these deficiencies.

Keywords: Accountability; Adherence; Availability; Cardiovascular disease medicines; Falsified and substandard medicines; Health-system strengthening; Low-income and middle-income countries; Patient-centered access.

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