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Review
. 2017 Feb;37(1):183-200.
doi: 10.1016/j.iac.2016.08.011.

The Angiotensin-Converting-Enzyme-Induced Angioedema

Murat Bas  1
Affiliations
Review

The Angiotensin-Converting-Enzyme-Induced Angioedema

Murat Bas. Immunol Allergy Clin North Am. 2017 Feb.

Abstract

The bradykinin B2 receptor antagonist icatibant is effective in angiotensin-converting enzyme inhibitor-induced angioedema. The drug is not approved officially for this indication and has to be administered in an emergency situation off-label. Corticosteroids or antihistamines do not seem to work in this condition. The effectiveness of C1-esterase-inhibitor in angiotensin-converting enzyme-induced angioedema must be verified in a double-blind study.

Keywords: ACE inhibitor; Angioedema; Bradykinin; Bradykinin receptors.

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