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Review
. 2017:237:1-21.
doi: 10.1007/164_2016_61.

Pathogenesis of COPD and Asthma

Clive Page  1 , Blaze O'Shaughnessy  2 , Peter Barnes  3
Affiliations
Review

Pathogenesis of COPD and Asthma

Clive Page et al. Handb Exp Pharmacol. 2017.

Abstract

Asthma and COPD remain two diseases of the respiratory tract with unmet medical needs. This review considers the current state of play with respect to what is known about the underlying pathogenesis of these two chronic inflammatory diseases of the lung. The review highlights why they are different conditions requiring different approaches to treatment and provides a backdrop for the subsequent chapters in this volume discussing recent advances in the pharmacology and treatment of asthma and COPD.

Keywords: Asthma; Bronchial hyperresponsiveness; COPD; Pathogenesis.

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