Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Sep-Oct;6(5):423-429.
doi: 10.4103/2231-0762.192936. Epub 2016 Oct 24.

Comparative evaluation of the efficacy of fluoride varnish and casein phosphopeptide - Amorphous calcium phosphate in reducing Streptococcus mutans counts in dental plaque of children: An in vivo study

Shweta Chandak  1 , Ashish Bhondey  1 , Amit Bhardwaj  2 , Jitesh Pimpale  3 , Manisha Chandwani  4
Affiliations

Comparative evaluation of the efficacy of fluoride varnish and casein phosphopeptide - Amorphous calcium phosphate in reducing Streptococcus mutans counts in dental plaque of children: An in vivo study

Shweta Chandak et al. J Int Soc Prev Community Dent. 2016 Sep-Oct.

Abstract

Aim: To assess the comparative efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complex visa viz. Streptococcus mutans in plaque, and thereby the role that these two agents could play in the prevention of dental caries.

Materials and methods: A cluster sample of 120 caries inactive individuals belonging to moderate and high caries risk group were selected from 3-5-year-old age group based on the criteria given by Krassee and were randomized to four groups, namely, fluoride varnish - Group I, CPP-ACP complex - Group II, mixture of CPP-ACP complex -Gourp III, and fluoride and routine oral hygiene procedures as control - Group IV. The results thus obtained were analyzed using Statistical Package for the Social Sciences (SPSS) version 16.

Results: A statistically significant difference in the pre and post-application scores of S. mutans (P < 0.01) count was observed in all the groups with CPP-ACP plus fluoride group being the most proficient.

Conclusion: Materials such as fluoride varnish, CPP-ACP, and CPP-ACP plus fluoride protects the tooth structure, preserving the integrity of primary dentition, with the most encouraging results being with CPP-ACP plus fluoride.

Keywords: Casein phosphopeptide–amorphous calcium phosphate (CPP–ACP); Streptococcus mutans; fluoride varnish.

PubMed Disclaimer

References

    1. Hu X, Fan M, Mulder J, Frencken JE. Caries experience in the primary dentition and presence of plaque in 7-year-old Chinese children: A 4 year timelag study. J Int Soc Prevent Communit Dent. 2015;5:205–10. - PMC - PubMed
    1. Kalra DD, Kalra RD, Kini PV, Allama Prabhu CR. Nonfluoride remineralization: An evidence-based review of contemporary technologies. J Dent Allied Sci. 2014;3:24–33.
    1. Van Houte J. Microbiological predictors of caries risk. Adv Dent Res. 1993;7:87–96. - PubMed
    1. Van Houte J. Role of microorganisms in caries etiology. J Dent Res. 1994;73:672–81. - PubMed
    1. Li Y, Tanner A. Effect of Antimicrobial Interventions on the Oral Microbiota Associated with Early Childhood Caries. Pediatr Dent. 2015;37:226–44. - PMC - PubMed

LinkOut - more resources