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Case Reports
. 2016 Oct;10(10):WD05-WD06.
doi: 10.7860/JCDR/2016/22772.8675. Epub 2016 Oct 1.

O'Brien's Granuloma- A Case Report

Pratik Mukesh Thacker  1 , Kashinath Nayak  2 , Flora Dorothy Lobo  3 , Pavithra Govindasamy  1
Affiliations
Case Reports

O'Brien's Granuloma- A Case Report

Pratik Mukesh Thacker et al. J Clin Diagn Res. 2016 Oct.

Abstract

Actinic granuloma is a self-limiting chronic disorder with elastolytic granulomas, mainly of the sun exposed skin and unknown pathogenesis. We report a case of a middle aged woman with multiple annular erythematous lesions. Histopathology revealed degenerated elastic fibres with histiocyte aggregates surrounded by multiple giant cells suggestive of elastolytic granulomas. She also had associated dyslipidemia and hypothyroidism. Actinic granuloma is relatively rare in the Indian population and needs to be differentiated from conditions like sarcoidosis and granuloma annulare.

Keywords: Actinic; Annular plaques; Elastolysis.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Annular lesions on hand.
[Table/Fig-2]:
[Table/Fig-2]:
Annular lesions on arm.
[Table/Fig-3]:
[Table/Fig-3]:
Annular lesions on upper back.
[Table/Fig-4]:
[Table/Fig-4]:
Thinned epidermis with degenerated elastic fibres with histiocyte aggregates surrounded by multiple giant cells. [H & E stain. x100].
[Table/Fig-5]:
[Table/Fig-5]:
Showing some degenerated elastic fibres (blue arrow). [Verhoef van Gieson stain x400].
See this image and copyright information in PMC

References

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