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Case Reports
. 2017 Sep/Oct;33(5):e114-e116.
doi: 10.1097/IOP.0000000000000833.

Conjunctival Melanoma Responsive to Combined Systemic BRAF/MEK Inhibitors

Lora R Dagi Glass  1 , Donald P Lawrence, Frederick A Jakobiec, Suzanne K Freitag
Affiliations
Case Reports

Conjunctival Melanoma Responsive to Combined Systemic BRAF/MEK Inhibitors

Lora R Dagi Glass et al. Ophthalmic Plast Reconstr Surg. 2017 Sep/Oct.

Abstract

This report demonstrates a unique case of conjunctival melanoma harboring a BRAF V600E mutation responsive to systemic therapy with BRAF and MEK inhibitors. While systemic therapy would not be appropriate in patients with local disease alone, it may act therapeutically in cases of higher stage ocular surface and eyelid melanoma.

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