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Review
. 2017 Jan:102:42-44.
doi: 10.1016/j.micpath.2016.11.016. Epub 2016 Nov 26.

Approach to osteomyelitis treatment with antibiotic loaded PMMA

Zhang Wentao  1 , Guangyu Lei  2 , Yang Liu  3 , Wei Wang  2 , Tao Song  1 , Jinzhu Fan  1
Affiliations
Review

Approach to osteomyelitis treatment with antibiotic loaded PMMA

Zhang Wentao et al. Microb Pathog. 2017 Jan.

Abstract

Background: To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to deliver high antibiotic concentrations at the infection site.

Objective: The objective of this review was to provide a literature review regarding approach to osteomyelitis treatment with antibiotic loaded PMMA.

Study design: Literature study regarding osteomyelitis treatment with antibiotic loaded carriers using key terms Antibiotic, osteomyelitis, biodegradable PMMA through published articles. Hands searching of bibliographies of identified articles were also undertaken.

Conclusion: We concluded that Antibiotic-impregnated PMMA beads are useful options for the treatment of osteomyelitis for prolonged drug therapy.

Keywords: Antibiotic; Biodegradable PMMA; Infection; Osteomyelitis.

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