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Comment
. 2016 Nov 29;48(12):1451-1452.
doi: 10.1038/ng.3727.

A DNA element that remembers winter

Chenlong Li  1 , Yuhai Cui  1   2
Affiliations
Comment

A DNA element that remembers winter

Chenlong Li et al. Nat Genet. .

Abstract

Polycomb-mediated silencing of the floral repressor gene FLC in response to long-term cold is a central event during vernalization in Arabidopsis thaliana, but how it is initiated is unclear. Two new studies identify a DNA element that mediates FLC silencing by attracting a pair of transcriptional repressors, VAL1 and VAL2, which in turn trigger epigenetic silencing by the Polycomb complex PHD-PRC2.

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References

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    1. Science. 2016 Jul 29;353(6298):485-8 - PubMed
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