Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Nov 29;13(11):e1002184.
doi: 10.1371/journal.pmed.1002184. eCollection 2016 Nov.

Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?

Marlieke E A de Kraker  1 , Andrew J Stewardson  2 , Stephan Harbarth  1
Affiliations

Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?

Marlieke E A de Kraker et al. PLoS Med. .

Abstract

Marlieke de Kraker and colleagues reflect on the need for better global estimates for the burden of antimicrobial resistance.

PubMed Disclaimer

Conflict of interest statement

I have read the journal's policy and have the following conflicts to report: SH and AJS participated in an investigator-initiated study on the burden of antimicrobial resistance (TIMBER) supported by an unrestricted research grant provided by Pfizer Europe and bioMérieux. SH is also a member of the Editorial Board of PLOS Medicine. AJS is an employee of Hand Hygiene Australia, a national quality improvement program, and is a member of the Healthcare Associated Infection Advisory Committee of the Australian Commission for Safety and Quality in Healthcare.

Figures

Fig 1
Fig 1. The distribution of hospital care level among hospitals reporting antimicrobial susceptibility and denominator data (subset of all hospitals) to EARS-Net (2013/2014) [6].
See this image and copyright information in PMC

References

    1. O'Neill J. Review on Antimicrobial Resistance Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations. London: Review on Antimicrobial Resistance; 2014. Available from: https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Ta...
    1. De Kraker MEA, Davey PG, Grundmann H. Mortality and Hospital Stay Associated with Resistant Staphylococcus aureus and Escherichia coli Bacteremia: Estimating the Burden of Antibiotic Resistance in Europe. PLoS Med. 2011; 8: e1001104 10.1371/journal.pmed.1001104 - DOI - PMC - PubMed
    1. Stewardson AJ, Allignol A, Beyersmann J, Graves N, Schumacher M, et al. The health and economic burden of bloodstream infections caused by antimicrobial-susceptible and non-susceptible Enterobacteriaceae and Staphylococcus aureus in European hospitals, 2010 and 2011: a multicentre retrospective cohort study. Eurosurveillance. 2016; 21: pii = 30319. - PMC - PubMed
    1. European Centre for Disease Prevention and Control (ECDC) and European Medicines Agency (EMEA) Joint Working Group. ECDC/ EMEA Joint Technical Report: The bacterial challenge: Time to react. Stockholm: ECDC. 2009. Available from: http://ecdc.europa.eu/en/publications/Publications/0909_TER_The_Bacteria...
    1. KPMG LLP. The global economic impact of anti-microbial resistance. London: KPMG LLP UK, research commissioned by the Wellcome Trust, as part of an independent review into anti-microbial resistance supported by the Department of Health and the Wellcome Trust. 2014. Available from: https://home.kpmg.com/content/dam/kpmg/pdf/2014/12/amr-report-final.pdf

Substances