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Clinical Trial
. 1989 Sep;28(3):366-8.
doi: 10.1111/j.1365-2125.1989.tb05440.x.

Yohimbine increases human salivary secretion

E Chatelut  1 , Y Rispail, M Berlan, J L Montastruc
Affiliations
Clinical Trial

Yohimbine increases human salivary secretion

E Chatelut et al. Br J Clin Pharmacol. 1989 Sep.

Abstract

The effect of oral yohimbine (14 mg) on salivary secretion was evaluated in healthy volunteers. Yohimbine significantly increased salivary secretion when compared with placebo. This effect was significant from 60 min until 180 min after administration under our experimental conditions. Yohimbine (or alpha 2-adrenoceptor blocking agents) could have a potential interest in the treatment of dry mouths.

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References

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