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. 2016 Nov;5(5):625-630.
doi: 10.3892/mco.2016.1003. Epub 2016 Aug 24.

Avoidance of unnecessary fine-needle aspiration with the use of the Thyroid Imaging Reporting Data System classification and strain elastography based on The Bethesda System for Reporting Thyroid Cytopathology

Murat Erkan  1 , Sule Canberk  1 , Gamze Z Kilicoglu  2 , Mine Onenerk  1 , Atay Uludokumaci  3 , Pembegul Gunes  1 , Tugba Atasoy  2
Affiliations

Avoidance of unnecessary fine-needle aspiration with the use of the Thyroid Imaging Reporting Data System classification and strain elastography based on The Bethesda System for Reporting Thyroid Cytopathology

Murat Erkan et al. Mol Clin Oncol. 2016 Nov.

Abstract

Thyroid fine-needle aspiration (FNA) biopsy has been widely accepted as an accurate and cost-effective tool in the management of thyroid nodules. To avoid unnecessary FNAs and provide appropriate management, patient evaluation should be based on a multidisciplinary approach. For this purpose, the Thyroid Imaging Reporting and Data System (TI-RADS) and strain elastography (SE) were proposed as tools for the risk assessment of malignancy in thyroid nodules. The aim of the present study was to analyze the utility of TI-RADS system and SE, along with FNA, and prospectively evaluate 369 consecutive patients referred for FNA of a thyroid nodule. TI-RADS was tested against The Bethesda System for Reporting Thyroid Cytopathology to determine whether there was an agreement between the two classification systems; statistically, some agreement was observed. Medians of the maximum SE values (E-max) were obtained for benign and malignant FNA results and found to be 1.97 [interquartile range (IQR): 1.87] and 2.8 (IQR: 3.42), respectively (P=0.004). The number of studies investigating the utility of TI-RADS and SE along with TBSRCT is currently limited. Our study demonstrated that a multidisciplinary approach with the use of TI-RADS and SE may mildly improve the management of thyroid nodules.

Keywords: Bethesda; Thyroid Imaging Reporting and Data System; elastography; thyroid fine-needle aspiration.

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Figures

Figure 1.
Figure 1.
Box plot shows E-max values of 261 benign and malignant (SFM/M) cases. x-axis and y-axis demonstrate benign and malignant cases according to TBSRTC and E-max values, respectively. The lower and upper ends of vertical lines are minimum and maximum E-max values. The upper edge of both boxes are the 75th percentile of the data set; lower end represents the 25th percentile. The line in the box shows the median.
Figure 2.
Figure 2.
Process flowchart. TI-RADS, Thyroid Imaging Reporting and Data System; FNA, fine-needle aspiration.
See this image and copyright information in PMC

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