Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Dec 1;5(1):105.
doi: 10.1186/s40249-016-0197-7.

Carrion's disease: an eradicable illness?

Cláudia Gomes  1 , Maria J Pons  2 , Juana Del Valle Mendoza  3 , Joaquim Ruiz  1
Affiliations

Carrion's disease: an eradicable illness?

Cláudia Gomes et al. Infect Dis Poverty. .

Abstract

Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion's disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion's disease, in which the illness is arriving to new areas, due to the expansion of the vector's distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination.

Keywords: Bartonella bacilliformis; Carrion’s disease; Colombia; Ecuador; Eradication; Neglected tropical diseases; Oroya fever; Peru; South America.

PubMed Disclaimer

References

    1. Anonymous Eradication of yaws - the Morges strategy. Wkly Epidemiol Rec. 2012;87:189–94. - PubMed
    1. International Task Force for Disease Eradication . Disease considered as candidates for global eradication by the International Task Force for Disease Eradication. 2008.
    1. Tanner M, Greenwood B, Whitty CJ, Ansah EK, Price RN, Dondorp AM, et al. Malaria eradication and elimination: views on how to translate a vision into reality. BMC Med. 2015;13:167. doi: 10.1186/s12916-015-0384-6. - DOI - PMC - PubMed
    1. Minnick MF, Anderson BE, Lima A, Battisti JM, Lawyer PG, Birtles RJ. Oroya fever and verrugaperuana: bartonelloses unique to South America. PLoS Negl Trop Dis. 2014;8:e2919. doi: 10.1371/journal.pntd.0002919. - DOI - PMC - PubMed
    1. Tarazona A, Maguiña C, Lopez de Guimaraes D, Montoya M, Pachas P. Terapia antibiótica para el manejo de la Bartonelosis o Enfermedad de Carrión en el Perú. Rev Peru Med Exp Salud Publ. 2006;23:188–200.