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. 2016 Dec 1;12(6):1207-1213.
doi: 10.5114/aoms.2015.51177. Epub 2016 Oct 24.

A new diagnostic tool for masked hypertension: impaired sleep quality

Fatma Erdem  1 , Ugur Cakır  2 , Osman Yıldırım  2 , Aytekin Alcelik  3 , Ibrahim Donmez  1 , Taha Can Tuman  2 , Sabri Onur Caglar  1 , Alim Erdem  1 , Mehmet Yazıcı  1
Affiliations

A new diagnostic tool for masked hypertension: impaired sleep quality

Fatma Erdem et al. Arch Med Sci. .

Abstract

Introduction: The aim of this study was to evaluate the relationship between masked hypertension and impaired sleep quality. Additionally, we evaluated the diagnostic role and prevalence of poor sleep quality among patients with newly diagnosed masked hypertension.

Material and methods: A total of 112 individuals, 72 patients with newly diagnosed masked hypertension and 40 normotensive healthy volunteers, were included in this study. All patients underwent evaluation comprising 12-lead electrocardiography, transthoracic echocardiography, 24-hour Holter ECG, and basic laboratory tests. Additionally, all participants completed questionnaires, including the Pittsburgh Sleep Quality Index (PSQI).

Results: The total PSQI score was significantly higher in the masked hypertension group than in the normotensive healthy volunteers (4.13 ±2.43 vs. 2.33 ±1.67, p < 0.001). A PSQI score > 5 was found in 45.8% (n = 33) of patients in the masked hypertension group and 15% (n = 6) of patients in the normotensive group (p < 0.001). The non-dipper pattern was found in 17.5% of the healthy volunteer group and 59.94% (n = 41) of the masked hypertension group (p < 0.001). When we compared the dipping pattern of the masked hypertension groups, there was a significant difference in PSQI score between the dipper and non-dipper groups (4.87 ±3.21 vs. 3.58 ±2.33, p < 0.001). Multiple logistic regression analyses showed that masked hypertension, LV mass, and LV mass index score were independent predictors of poor PSQI.

Conclusions: This study demonstrates impaired sleep quality in subjects with masked hypertension, particularly those with a non-dipper pattern. Additionally, this study indicates that impaired sleep quality may help diagnose masked hypertension, particularly in the non-dipper group.

Keywords: masked hypertension; sleep disturbances; sleep quality.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Recruitment, exclusion, and subsequent grouping of all patients
Figure 2
Figure 2
Distribution of PSQI scores in MHT group and normotensive healthy subjects
See this image and copyright information in PMC

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