Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2017 Apr;44(4):505-511.
doi: 10.3899/jrheum.161003. Epub 2016 Dec 1.

Sustained Benefits of Exercise-based Motivational Interviewing, but Only among Nonusers of Opioids in Patients with Fibromyalgia

Sunghye Kim  1   2 , James E Slaven  1   2 , Dennis C Ang  3   4
Affiliations
Randomized Controlled Trial

Sustained Benefits of Exercise-based Motivational Interviewing, but Only among Nonusers of Opioids in Patients with Fibromyalgia

Sunghye Kim et al. J Rheumatol. 2017 Apr.

Abstract

Objective: Given the known side effects of opioids and their potential effects on cognition, we sought to evaluate the benefits of motivational interviewing (MI) to promote physical activity on 2 subsets of participants with fibromyalgia (FM): nonusers and users of opioids.

Methods: This was a secondary data analysis of a 36-week randomized controlled trial to assess the efficacy of MI to promote physical activity among participants with FM. Participants were randomized to 1 of 2 treatment arms: 6 phone-based MI sessions (n = 107) or 6 sessions of FM self-management instructions [attention control (AC), n = 109]. The primary outcomes were changes in physical function (Medical Outcomes Study Short Form-36), pain severity (Brief Pain Inventory), global FM symptom severity (Fibromyalgia Impact Questionnaire), and the amount of light to moderate physical activity (LMPA) from baseline to each followup visit. At study entry, subjects were categorized as opioid nonusers versus users. Repeated measures ANOVA was used to assess treatment effects adjusting for potential confounders.

Results: Of the 216 participants, 145 (67%) were nonusers and 71 (33%) were opioid users. Among nonusers, MI was associated with improved physical function, reduced pain severity, and global FM severity, and increased LMPA at 6-month followup. Among opioid users, there were no significant differences in any outcome measures between the MI and AC groups.

Conclusion: Exercise-based MI was associated with sustained clinical benefits 6 months after completion of therapy, but only for those who were not taking opioids.

Keywords: FIBROMYALGIA; MOTIVATIONAL INTERVIEWING; OPIOID RISK; TREATMENT MODERATOR.

PubMed Disclaimer

Conflict of interest statement

There is no conflicts of interested indicated by the authors.

Figures

Figure 1
Figure 1. Flow of Participants in the Parent Trial
See this image and copyright information in PMC

Comment in

References

    1. Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008;58:26–35. - PMC - PubMed
    1. Skaer TL. Fibromyalgia: disease synopsis, medication cost effectiveness and economic burden. Pharmacoeconomics. 2014;32:457–66. - PubMed
    1. Bidonde J, Busch AJ, Bath B, Milosavljevic S. Exercise for adults with fibromyalgia: an umbrella systematic review with synthesis of best evidence. Curr Rheumatol Rev. 2014;10:45–79. - PubMed
    1. Segura-Jimenez V, Alvarez-Gallardo IC, Estevez-Lopez F, Soriano-Maldonado A, Delgado-Fernandez M, Ortega FB, et al. Differences in sedentary time and physical activity between female patients with fibromyalgia and healthy controls: the al-Andalus project. Arthritis Rheumatol. 2015;67:3047–57. - PubMed
    1. Dobkin PL, Da Costa D, Abrahamowicz M, Dritsa M, Du Berger R, Fitzcharles MA, et al. Adherence during an individualized home based 12-week exercise program in women with fibromyalgia. J Rheumatol. 2006;33:333–41. - PubMed

Publication types

Substances

LinkOut - more resources