Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion
- PMID: 27911147
- PMCID: PMC5133344
- DOI: 10.1210/en.2016-1797
Zinc Transport Gets Its Zing Back: Double-Knockout of ZnT7 and ZnT8 Reveals the Importance of Zinc Transporters to Insulin Secretion
Comment on
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Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.Endocrinology. 2016 Dec;157(12):4534-4541. doi: 10.1210/en.2016-1573. Epub 2016 Oct 18. Endocrinology. 2016. PMID: 27754787 Free PMC article.
References
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- Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science. 2007;316(5829):1331–1336. - PubMed
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- Blundell TL, Cutfield JF, Cutfield SM, et al. Atomic positions in rhombohedral 2-zinc insulin crystals. Nature. 1971;231(5304):506–511. - PubMed
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