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Comment
. 2016 Dec 13;113(50):14173-14175.
doi: 10.1073/pnas.1617112113. Epub 2016 Nov 30.

Noninvasive prenatal testing to analyze the fetal genome

Mary E Norton  1
Affiliations
Comment

Noninvasive prenatal testing to analyze the fetal genome

Mary E Norton. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

M.E.N.’s research receives support from Natera.

Figures

Fig. 1.
Fig. 1.
An overview of currently available applications of massively parallel sequencing-based noninvasive prenatal testing using cell-free nucleic acids (DNA and RNA) in maternal plasma thought to originate from apoptotic trophoblasts. The fetal genome (from chromosomal to subchromosomal to single-gene levels) may be decoded; the methylome and transcriptome have also been investigated. A, adenine; C, cytosine; G, guanosine; mC, methylated cytosine; MPS, massively parallel sequencing; RNA-seq, RNA sequencing; T, thymine; U, uridine. Reproduced from ref. , with permission of Annual Review of Medicine, Volume 67 © 2016 by Annual Reviews.
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