Fetal to Adult Hematopoiesis with the "Flk" of a Switch
- PMID: 27912084
- DOI: 10.1016/j.stem.2016.11.013
Fetal to Adult Hematopoiesis with the "Flk" of a Switch
Abstract
Blood development relies on discrete stem and progenitor cell populations with unclear lineage relationships and distinct functional characteristics that change during ontogeny. In this issue of Cell Stem Cell, Beaudin et al. (2016) identify a hematopoietic stem cell population with fetal characteristics that is developmentally restricted yet capable of long-term multi-lineage reconstitution upon transplantation into adult recipients.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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A Transient Developmental Hematopoietic Stem Cell Gives Rise to Innate-like B and T Cells.Cell Stem Cell. 2016 Dec 1;19(6):768-783. doi: 10.1016/j.stem.2016.08.013. Epub 2016 Sep 22. Cell Stem Cell. 2016. PMID: 27666010 Free PMC article.
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