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Comment
. 2016 Nov;24(11):1892-1894.
doi: 10.1038/mt.2016.193.

Devouring the Hematopoietic Stem Cell: Setting the Table for Marrow Cell Transplantation

Morton J Cowan  1 , Hans-Peter Kiem  2
Affiliations
Comment

Devouring the Hematopoietic Stem Cell: Setting the Table for Marrow Cell Transplantation

Morton J Cowan et al. Mol Ther. 2016 Nov.
No abstract available

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Figures

Figure 1
Figure 1
”Setting the table” for engraftment of donor hematopoietic stem cells (HSCs). (a) Antibody-dependent cell-mediated phagocytosis–mediated “devouring” of HSCs with anti-CD47 blocking a “don't eat me” signal. (b) Antibody-mediated killing of HSCs by saporin (SAP) via blocking of protein synthesis. SIRPα, signal regulatory protein α.
See this image and copyright information in PMC

Comment on

References

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