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. 2016 Nov 17;21(46):30402.
doi: 10.2807/1560-7917.ES.2016.21.46.30402.

Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016

Denise Antona  1 , Manoëlle Kossorotoff  2 , Isabelle Schuffenecker  3 , Audrey Mirand  4 , Marianne Leruez-Ville  5 , Clément Bassi  6 , Mélodie Aubart  2 , Florence Moulin  7 , Daniel Lévy-Bruhl  1 , Cécile Henquell  4 , Bruno Lina  3 , Isabelle Desguerre  2
Affiliations

Severe paediatric conditions linked with EV-A71 and EV-D68, France, May to October 2016

Denise Antona et al. Euro Surveill. .

Abstract

We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation.

Keywords: Enterovirus A71; Enterovirus D68; France; children; severe neurological symptoms.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure
Figure
Distribution of severe paediatric cases linked with EV infections over time, by enterovirus genotype and week of symptoms onset, Metropolitan France, May–October 2016 (n=59)
See this image and copyright information in PMC

References

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