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. 2017 Sep;27(5):806-810.
doi: 10.1080/14397595.2016.1265705. Epub 2016 Dec 16.

Total knee arthroplasty improves both knee function and disease activity in patients with rheumatoid arthritis

Ken Kumagai  1 , Kengo Harigane  1 , Yoshihiro Kusayama  1 , Taro Tezuka  1 , Yutaka Inaba  1 , Tomoyuki Saito  1
Affiliations

Total knee arthroplasty improves both knee function and disease activity in patients with rheumatoid arthritis

Ken Kumagai et al. Mod Rheumatol. 2017 Sep.

Abstract

Objective: This study evaluated the effect of TKA with capsulosynovectomy on disease activity and knee function in patients with RA.

Methods: Seventy-six RA patients who underwent primary TKA with more than two years of follow-up were retrospectively reviewed to assess postoperative knee function and disease activity.

Results: Postoperative knee function was significantly improved in all clinical scores, and maintained up to 24 months after surgery. RA disease activity was significantly decreased in DAS28-CRP, CDAI, and serum CRP level, and maintained up to 24 months after surgery. Postoperative knee function was negatively correlated with RA disease activity.

Conclusions: TKA improves both knee function and disease activity in patients with rheumatoid arthritis.

Keywords: Disease activity; Knee function; Rheumatoid arthritis; Total knee arthroplasty.

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