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. 2016 Dec 6:3:160110.
doi: 10.1038/sdata.2016.110.

A phenome-wide examination of neural and cognitive function

R A Poldrack  1 , E Congdon  2 , W Triplett  1 , K J Gorgolewski  1 , K H Karlsgodt  2   3 , J A Mumford  4 , F W Sabb  5 , N B Freimer  2 , E D London  2 , T D Cannon  6   7 , R M Bilder  2   3
Affiliations

A phenome-wide examination of neural and cognitive function

R A Poldrack et al. Sci Data. .

Abstract

This data descriptor outlines a shared neuroimaging dataset from the UCLA Consortium for Neuropsychiatric Phenomics, which focused on understanding the dimensional structure of memory and cognitive control (response inhibition) functions in both healthy individuals (130 subjects) and individuals with neuropsychiatric disorders including schizophrenia (50 subjects), bipolar disorder (49 subjects), and attention deficit/hyperactivity disorder (43 subjects). The dataset includes an extensive set of task-based fMRI assessments, resting fMRI, structural MRI, and high angular resolution diffusion MRI. The dataset is shared through the OpenfMRI project, and is formatted according to the Brain Imaging Data Structure (BIDS) standard.

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Conflict of interest statement

The authors declare no competing financial interests.

Figures

Figure 1
Figure 1. Distribution of selected QC measures for T1w anatomical scans included in dataset.
Figure 2
Figure 2. Distribution of selected QC measures for BOLD contrast functional scans included in dataset.
Figure 3
Figure 3. Results from the semi-automated DWI quality assessment, by subject group.
See this image and copyright information in PMC

Dataset use reported in

  • doi: 10.1073/pnas.1321728111
  • doi: 10.1016/j.pscychresns.2014.02.002
  • doi: 10.3389/fnins.2013.00173
  • doi: 10.1016/j.nicl.2015.08.006
  • doi: 10.1093/cercor/bht304
  • doi: 10.1093/scan/nst114

References

Data Citations

    1. Bilder R. 2016. OpenfMRI. ds000030

References

    1. Helfinstein S. M. et al. Predicting risky choices from brain activity patterns. Proc. Natl. Acad. Sci. USA 111, 2470–2475 (2014). - PMC - PubMed
    1. Congdon E. et al. Neural activation during response inhibition in adult attention-deficit/hyperactivity disorder: preliminary findings on the effects of medication and symptom severity. Psychiatry Res. 222, 17–28 (2014). - PMC - PubMed
    1. Congdon E. et al. Differences in neural activation as a function of risk-taking task parameters. Front. Neurosci. 7, 173 (2013). - PMC - PubMed
    1. Montojo C. A. et al. Neural mechanisms of response inhibition and impulsivity in 22q11.2 deletion carriers and idiopathic attention deficit hyperactivity disorder. Neuroimage Clin. 9, 310–321 (2015). - PMC - PubMed
    1. Montojo C. A. et al. Neural substrates of inhibitory control deficits in 22q11.2 deletion syndrome. Cereb. Cortex 25, 1069–1079 (2015). - PMC - PubMed

Publication types