Neutrophils are not required for resolution of acute gouty arthritis in mice

Laurent L Reber^{1

2

3}, Nicolas Gaudenzio^{1

4}, Philipp Starkl^{1

5}, Stephen J Galli^{1

4

6}

Affiliations

¹ Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
² Département d'Immunologie, Unité des Anticorps en Thérapie et Pathologie, Institut Pasteur, Paris, France.
³ Institut National de la Santé et de la Recherche Médicale, U1222, Paris, France.
⁴ Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, California, USA.
⁵ CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, and Department of Medicine I, Research Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.
⁶ Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.

Comment

Laurent L Reber et al. Nat Med. 2016.

. 2016 Dec 6;22(12):1382-1384.

doi: 10.1038/nm.4216.

Laurent L Reber^{1

2

3}, Nicolas Gaudenzio^{1

4}, Philipp Starkl^{1

5}, Stephen J Galli^{1

4

6}

¹ Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
² Département d'Immunologie, Unité des Anticorps en Thérapie et Pathologie, Institut Pasteur, Paris, France.
³ Institut National de la Santé et de la Recherche Médicale, U1222, Paris, France.
⁴ Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, California, USA.
⁵ CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, and Department of Medicine I, Research Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria.
⁶ Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, USA.

No abstract available

Comment in

Reply to "Neutrophils are not required for resolution of acute gouty arthritis in mice".
Reinwald C, Schauer C, Csepregi JZ, Kienhöfer D, Weidner D, Malissen M, Mocsai A, Schett G, Herrmann M, Hoffmann M. Reinwald C, et al. Nat Med. 2016 Dec 6;22(12):1384-1386. doi: 10.1038/nm.4217. Nat Med. 2016. PMID: 27923022 No abstract available.

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines.
Schauer C, Janko C, Munoz LE, Zhao Y, Kienhöfer D, Frey B, Lell M, Manger B, Rech J, Naschberger E, Holmdahl R, Krenn V, Harrer T, Jeremic I, Bilyy R, Schett G, Hoffmann M, Herrmann M. Schauer C, et al. Nat Med. 2014 May;20(5):511-7. doi: 10.1038/nm.3547. Epub 2014 Apr 28. Nat Med. 2014. PMID: 24784231