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. 2017 Apr;15(4):597-599.
doi: 10.1016/j.cgh.2016.11.028. Epub 2016 Dec 3.

Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Patients With Inflammatory Bowel Disease: A Single-Center Experience

Samantha M Chin  1 , Jenny Sauk  2 , Jasmine Mahabamunuge  3 , Jess L Kaplan  4 , Elizabeth L Hohmann  3 , Hamed Khalili  5
Affiliations

Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in Patients With Inflammatory Bowel Disease: A Single-Center Experience

Samantha M Chin et al. Clin Gastroenterol Hepatol. 2017 Apr.
No abstract available

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Conflict of interest statement

Conflict of Interest: None to declare

Figures

Figure 1
Figure 1. Characteristics and outcomes of patients with IBD undergoing FMT for rCDI
A) Baseline characteristics of patients with IBD that underwent FMT. *Smoking information was missing for 1 (3%) patient. † Children less than 12 years old (n=1, 3%) were not included; BMI was missing for 6 (17%) patients. †† Previous GI surgeries included colectomy with IPAA, colostomy, diverting colostomy, small bowel resection, fistula repair, cholecystectomy, and appendectomy. B) Outcomes of patients with IBD that underwent FMT for recurrent CDI. § CDI recurrence within 2 months of FMT treatment. ¶ Treatment escalation included new IBD medications or an increase in dosage. # Surgical interventions included a diverting ileostomy and total proctocolectomy.
See this image and copyright information in PMC

References

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    1. Youngster I, Sauk J, Pindar C, et al. Fecal microbiota transplant for relapsing Clostridium difficile infection using a frozen inoculum from unrelated donors: a randomized, open-label, controlled pilot study. Clin Infect Dis. 2014;58:1515–1522. - PMC - PubMed
    1. Nguyen GC, Kaplan GG, Harris ML, et al. A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients. Am J Gastroenterol. 2008;103:1443–1450. - PubMed
    1. Moayyedi P, Surette MG, Kim PT, et al. Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial. Gastroenterology. 2015;149:102–109. e6. - PubMed
    1. Rossen NG, Fuentes S, van der Spek MJ, et al. Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis. Gastroenterology. 2015;149:110–118. e4. - PubMed

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