Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index
- PMID: 27924103
- PMCID: PMC5417334
- DOI: 10.1038/ajg.2016.485
Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index
Abstract
Frailty is a key determinant of outcomes in patients with cirrhosis. Two papers in this issue of the American Journal of Gastroenterology advance our understanding of the mechanism by which frailty impacts mortality-by increasing the risk of hospitalization for liver-related complications. We now have overwhelming justification to incorporate frailty into clinical practice, but this should be done in a systematic way to foster multi-center collaboration to accelerate research in this field. It is time for consensus on single frailty index to unify decision-making surrounding frailty and equalize outcomes for all cirrhotics across all centers.
Conflict of interest statement
Guarantor of article : Jennifer C. Lai, MD, MBASpecific author contributions : Dr. Lai drafted this entire editorial and approved the final draft submitted.Financial support : This editorial was supported in part by an American College of Gastroenterology Junior Faculty Development Award, P30AG044281 (UCSF Older Americans Independence Center), K23AG048337 (Paul B. Beeson Career Development Award in Aging Research), and the American Federation for Aging Research. These funding agencies played no role in the preparation of this editorial.Potential competing interests : None
Comment on
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A Rapid Bedside Screen to Predict Unplanned Hospitalization and Death in Outpatients With Cirrhosis: A Prospective Evaluation of the Clinical Frailty Scale.Am J Gastroenterol. 2016 Dec;111(12):1759-1767. doi: 10.1038/ajg.2016.303. Epub 2016 Aug 2. Am J Gastroenterol. 2016. PMID: 27481305
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Frailty as Tested by Gait Speed is an Independent Risk Factor for Cirrhosis Complications that Require Hospitalization.Am J Gastroenterol. 2016 Dec;111(12):1768-1775. doi: 10.1038/ajg.2016.336. Epub 2016 Aug 30. Am J Gastroenterol. 2016. PMID: 27575708
References
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- Dunn MA, Josbeno DA, Tevar AD, et al. Frailty as tested by gait speed is an independent risk factor for cirrhosis complications that require hospitalization. Am J Gastroenterol - PubMed
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- Tandon P, Tangri N, Thomas L, et al. A rapid bedside screen to predict unplanned hospitalization and death in outpatients with cirrhosis: a prospective evaluation of the Clinical Frailty Scale. Am J Gastroenterol - PubMed
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- Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):146–156. - PubMed
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