Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Feb;90(1070):20160542.
doi: 10.1259/bjr.20160542. Epub 2016 Dec 7.

Evaluation of background parenchymal enhancement on breast MRI: a systematic review

Bianca Bignotti  1 , Alessio Signori  2 , Francesca Valdora  3 , Federica Rossi  4 , Massimo Calabrese  5 , Manuela Durando  6 , Giovanna Mariscotto  6 , Alberto Tagliafico  2   5
Affiliations

Evaluation of background parenchymal enhancement on breast MRI: a systematic review

Bianca Bignotti et al. Br J Radiol. 2017 Feb.

Abstract

Objective: To perform a systematic review of the methods used for background parenchymal enhancement (BPE) evaluation on breast MRI.

Methods: Studies dealing with BPE assessment on breast MRI were retrieved from major medical libraries independently by four reviewers up to 6 October 2015. The keywords used for database searching are "background parenchymal enhancement", "parenchymal enhancement", "MRI" and "breast". The studies were included if qualitative and/or quantitative methods for BPE assessment were described.

Results: Of the 420 studies identified, a total of 52 articles were included in the systematic review. 28 studies performed only a qualitative assessment of BPE, 13 studies performed only a quantitative assessment and 11 studies performed both qualitative and quantitative assessments. A wide heterogeneity was found in the MRI sequences and in the quantitative methods used for BPE assessment.

Conclusion: A wide variability exists in the quantitative evaluation of BPE on breast MRI. More studies focused on a reliable and comparable method for quantitative BPE assessment are needed. Advances in knowledge: More studies focused on a quantitative BPE assessment are needed.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
A flowchart of the selection of studies. BPE, background parenchymal enhancement.
See this image and copyright information in PMC

References

    1. European Society of Radiology (ESR). Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging 2015; 6: 141–55. doi: https://doi.org/10.1007/s13244-015-0394-0 - DOI - PMC - PubMed
    1. European Society of Radiology (ESR). Medical imaging in personalised medicine: a white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging 2011; 2: 621–30. - PMC - PubMed
    1. National Research Council (US) Committee on A Framework for Developing a New Taxonomy of Disease. Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease. Washington (DC): National Academies Press (US); 2011. - PubMed
    1. Herold CJ, Lewin JS, Wibmer AG, Thrall JH, Krestin GP, Dixon AK, et al. . Imaging in the age of precision medicine: summary of the proceedings of the 10th biannual symposium of the international society for strategic studies in radiology. Radiology 2015; 279: 226–38. - PubMed
    1. Sullivan DC, Obuchowski NA, Kessler LG, Raunig DL, Gatsonis C, Huang EP, et al. . Metrology standards for quantitative imaging biomarkers. Radiology 2015; 277: 813–25. doi: https://doi.org/10.1148/radiol.2015142202 - DOI - PMC - PubMed

Publication types

MeSH terms