Immunoglobulin therapy
- PMID: 27927824
- PMCID: PMC6297324
- DOI: 10.7861/clinmedicine.16-6-576
Immunoglobulin therapy
Abstract
Immunoglobulin is an expensive blood product of potentially limited supply used in a wide variety of medical conditions, across a number of specialties. Historically, immunoglobulin has been associated with transmission of blood borne infection (eg hepatitis C). Immunoglobulin use needs to be carefully considered, appropriately prescribed and recorded. The Department of Health, in conjunction with relevant stakeholders, has established a demand management programme to secure immunoglobulin supplies for patients most in need of treatment and to limit use for indications where evidence is lacking.
Keywords: Blood product; demand management; immunoglobulin; immunomodulatory; replacement.
© Royal College of Physicians 2016. All rights reserved.
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References
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- Lucas M. Lee M. Lortan J, et al. Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years. J Allergy Clin Immunol. 2010;125:1354–60.e4. - PubMed
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- Cherin P. Belizna C. Cartry O, et al. Long-term subcutaneous immunoglobulin use in inflammatory myopathies: A retrospective review of 19 cases. Autoimmun Rev. 2016;15:281–6. - PubMed
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