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Practice Guideline
. 2017 Jan 11;96(1):24-45.
doi: 10.4269/ajtmh.16-84256. Epub 2016 Dec 7.

Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH)

Affiliations
Practice Guideline

Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH)

Naomi Aronson et al. Am J Trop Med Hyg. .
No abstract available

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Conflict of interest statement

Potential Conflict of Interest: The following list is a reflection of what has been reported to IDSA. To provide thorough transparency, IDSA requires full disclosure of all relationships, regardless of relevancy to the guideline topic. Evaluation of such relationships as potential conflicts of interest (COI) is determined by a review process that includes assessment by the SPGC Chair, the SPGC liaison to the development Panel, the Board of Directors liaison to the SPGC, and, if necessary, the Conflict of Interest (COI) Task Force of the Board. This assessment of disclosed relationships for possible COI will be based on the relative weight of the financial relationship (i.e., monetary amount) and the relevance of the relationship (i.e., the degree to which an association might reasonably be interpreted by an independent observer as related to the topic or recommendation of consideration). The reader of these guidelines should be mindful of this when the list of disclosures is reviewed. For activities outside of the submitted work, N.A. has received payment from Up to Date. For activities outside of the submitted work M.E. has received research grants from the Israel National Institute for Health Policy Research (Rotavirus). For activities outside of the submitted work, R.P. has received personal fees from Merck & Co, Inc. and has a patent Protozoacidal Activity of the Phenothiazines (U.S. patent number 4,407,800), 1983.issued. No conflicts: E.C., M.L., R.L., B.H., P.W., S.J., and A.M.

Figures

Figure 1:
Figure 1:
Approach and implications to rating the quality of evidence and strength of recommendations using the GRADE methodology (unrestricted use of the figure granted by the U.S. GRADE Network) [1]
Figure 2:
Figure 2:
Maps of the Geographic Distribution of Cutaneous Leishmaniasis (CL). Notes: Adapted and modified from Chapter 277, Leishmania species. Principles and Practice of Infectious Diseases [31] 1In Guatemala, the reported cases of CL have been acquired in the northern departments (particularly, El Petén and Alta Verapaz but also Izabal, El Quiché, Baja Verapaz, and Jalapa). 2The etiologic agents of CL in Israel primarily include L. major and L. tropica but also L. infantum-chagasi. 3The species L. (Leishmania) martiniquensis, which was formally named in 2014, has been identified as the etiologic agent of cutaneous and visceral leishmaniasis in the French West Indies (Martinique Island) and Thailand, where it previously was referred to as “L. siamenensis” (not considered a taxonomically valid name). 4In Sri Lanka, L. donovani has been identified as the etiologic agent of cutaneous and visceral leishmaniasis. 5Not all Leishmania species that cause CL are included in this map (eg, L. amazonensis in South America).
Figure 3:
Figure 3:
Maps of the Geographic Distribution of Visceral Leishmaniasis (VL)

References

    1. Guyatt GH, Oxman AD, Vist GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ (Clinical research ed) 2008;336(7650):924–6. - PMC - PubMed
    1. Magill A. Principles and practice of infectious diseases. 8th ed. Philadelphia, PA: Elsevier; 2015. Leishmania species. Chapter 277; pp. 3091–107.
    1. World Health Organization . Vol. 949. Geneva, Switzerland: WHO; 2010. Control of the leishmaniases. World Health Organization technical report series. xii-xiii, 1–186, back cover. - PubMed
    1. Sundar S, Mehta H, Suresh AV, Singh SP, Rai M, Murray HW. Amphotericin B treatment for Indian visceral leishmaniasis: conventional versus lipid formulations. Clin Infect Dis. 2004;38:377–83. - PubMed
    1. Laguna F, Videla S, Jimenez-Mejias ME, et al. Amphotericin B lipid complex versus meglumine antimoniate in the treatment of visceral leishmaniasis in patients infected with HIV: a randomized pilot study. J Antimicrob Chemother. 2003;52:464–8. - PubMed

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