Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jan;10(1):37-39.
doi: 10.1111/1751-7915.12463. Epub 2016 Dec 8.

The renaissance of life near the boiling point - at last, genetics and metabolic engineering

Michael W W Adams  1 , Robert M Kelly  2
Affiliations

The renaissance of life near the boiling point - at last, genetics and metabolic engineering

Michael W W Adams et al. Microb Biotechnol. 2017 Jan.

Abstract

We discuss here the prospects for biotechnology of extreme thermophilic microorganisms.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Hot spring in Yellowstone National Park, USA.
Figure 2
Figure 2
Isolation of thermophilic species in the 20th century. Those that now have genetic systems are circled (red for bacteria and black for archaea).
See this image and copyright information in PMC

References

    1. Bridger, S.L. , Lancaster, W.A. , Poole, F.L. 2nd , Schut, G.J. , and Adams, M.W. (2012) Genome sequencing of a genetically tractable Pyrococcus furiosus strain reveals a highly dynamic genome. J Bacteriol 194: 4097–4106. - PMC - PubMed
    1. Hawkins, A.B. , Lian, H. , Zeldes, B.M. , Loder, A.J. , Lipscomb, G.L. , Schut, G.J. , et al (2015) Bioprocessing analysis of Pyrococcus furiosus strains engineered for CO(2)‐based 3‐hydroxypropionate production. Biotechnol Bioeng 112: 1533–1543. - PMC - PubMed
    1. Kataeva, I.A. , Yang, S.J. , Dam, P. , Poole, F.L. 2nd , Yin, Y. , Zhou, F. , et al (2009) Genome sequence of the anaerobic, thermophilic, and cellulolytic bacterium “Anaerocellum thermophilum” DSM 6725. J Bacteriol 191: 3760–3761. - PMC - PubMed
    1. Keller, M.W. , Schut, G.J. , Lipscomb, G.L. , Menon, A.L. , Iwuchukwu, I.J. , Leuko, T.T. , et al (2013) Exploiting microbial hyperthermophilicity to produce an industrial chemical, using hydrogen and carbon dioxide. Proc Natl Acad Sci USA 110: 5840–5845. - PMC - PubMed
    1. Keller, M.W. , Lipscomb, G.L. , Loder, A.J. , Schut, G.J. , Kelly, R.M. , and Adams, M.W. (2015) A hybrid synthetic pathway for butanol production by a hyperthermophilic microbe. Metab Eng 27: 101–106. - PubMed

Publication types

MeSH terms

LinkOut - more resources