Medicinal plants and natural products in amelioration of arsenic toxicity: a short review
- PMID: 27931138
- PMCID: PMC6130623
- DOI: 10.1080/13880209.2016.1235207
Medicinal plants and natural products in amelioration of arsenic toxicity: a short review
Erratum in
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Corrigendum.Pharm Biol. 2017 Dec;55(1):847. doi: 10.1080/13880209.2017.1284400. Pharm Biol. 2017. PMID: 28140739 Free PMC article. No abstract available.
Abstract
Context: Chronic arsenic toxicity (arsenicosis) is considered a serious public health menace worldwide, as there is no specific, safe, and efficacious therapeutic management of arsenicosis.
Objectives: To collate the studies on medicinal plants and natural products with arsenic toxicity ameliorative effect, active pre-clinically and/or clinically.
Methods: Literature survey was carried out by using Google, Scholar Google and Pub-Med. Only the scientific journal articles found on the internet for last two decades were considered. Minerals and semi-synthetic or synthetic analogs of natural products were excluded.
Results: Literature study revealed that 34 medicinal plants and 14 natural products exhibited significant protection from arsenic toxicity, mostly in preclinical trials and a few in clinical studies.
Conclusion: This research could lead to development of a potentially useful agent in clinical management of arsenicosis in humans.
Keywords: Arsenicosis; antioxidant; ascorbic acid; clinical; curcumin.
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