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. 2016 Dec;48(10):3292-3298.
doi: 10.1016/j.transproceed.2016.09.041.

Incidence of Diabetes Mellitus After Kidney Transplantation in Slovakia: Multicentric, Prospective Analysis

I Dedinská  1 , T Baltesová  2 , Ĺ Beňa  2 , M Čellár  3 , P Galajda  4 , M Chrastina  5 , A Jurčina  2 , L Kováčiková  6 , Ľ Laca  1 , E Lacková  2 , S Lauková Valachová  1 , J Miklušica  7 , J Rosenberger  2 , M Sersenová  5 , P Skalová  1 , Z Žilinská  5 , M Mokáň  4
Affiliations

Incidence of Diabetes Mellitus After Kidney Transplantation in Slovakia: Multicentric, Prospective Analysis

I Dedinská et al. Transplant Proc. 2016 Dec.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Transplant Proc. 2017 Jan-Feb;49(1):237. doi: 10.1016/j.transproceed.2016.12.011. Transplant Proc. 2017. PMID: 28104148 No abstract available.

Abstract

Background: The incidence rate of post-transplant diabetes mellitus (PTDM) after kidney transplantation (KT) is 5% to 40%. The objective of this analysis was to identify the risk factors of PTDM after KT in the Slovak Republic (SR).

Methods: In the group of 133 patients/non-diabetics, we identified the risk factors of PTDM in the monitored period of 12 months from transplantation.

Results: The incidence of PTDM in the SR in 2014 was 38.3%. By logistic regression, we discovered that the age at the time of KT [odds ratio, 1.0885; 95% CI, 1.0222-1.1592; P = .0082], the value of body mass index (BMI) at the time of KT [odds ratio, 1.4606; 95% CI, 1.0099-2.1125; P = .0442], and the value of insulin resistance index (homeostatic model assessment for insulin resistance) at the time of KT [odds ratio, 2.5183; 95% CI, 1.7119-3.4692; P < .0001] represented predictive factors of PTDM. The independent risk factors of PTDM in our group were age at the time of KT of more than 60 years [HR 0.3871; 95% CI 0.1659-1.7767; P = .0281], waist circumference at the time of KT in men more than 94 cm and in women more than 80 cm [HR, 3.4833; 95% CI, 1.2789-9.4878 (P = .0146)], BMI at the time of KT [HR 3.0011; 95% CI 1.0725-8.3977 (P = .0363)], and triacylglycerols at the time of KT more than 1.7 mmol/L [HR, 2.9763; 95% CI, 1.0141-8.7352; P = .0471].

Conclusions: In the group of Slovak patients after kidney transplantation, the dominating risk factor for PTDM development was insulin resistance prior to KT.

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