Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Oct;83(3):274-6.
doi: 10.1007/BF00285171.

Correlation between chromosomal breakpoint positions and synaptic behaviour in human males heterozygous for a pericentric inversion

A de Perdigo  1 , O Gabriel-Robez, Y Rumpler
Affiliations

Correlation between chromosomal breakpoint positions and synaptic behaviour in human males heterozygous for a pericentric inversion

A de Perdigo et al. Hum Genet. 1989 Oct.

Abstract

The examination of synaptic data and localization of chromosomal breakpoints in a review of human pericentric inversions suggest that synaptic and recombination behaviour in rearranged chromosomes during meiosis can be predicted by determining the subband in which the breakpoint is located. According to this hypothesis, it can be postulated that loops in pericentric inversions are routinely formed only in cases when both breaks occur in G-light bands, with the genetic consequences of crossing-over. In other cases, heterosynapsis is accomplished without previous homosynapsis, thereby minimizing the production of unbalanced gametes.

PubMed Disclaimer

References

    1. Ann Genet. 1986;29(3):129-68 - PubMed
    1. J Cell Sci. 1984 Oct;71:159-76 - PubMed
    1. Hum Genet. 1987 May;76(1):81-9 - PubMed
    1. Chromosoma. 1961;12:97-115 - PubMed
    1. Ann Hum Genet. 1986 Oct;50(Pt 4):369-83 - PubMed

Publication types