Twisting IL-1 signaling to kill CML stem cells
- PMID: 27932325
- DOI: 10.1182/blood-2016-10-741009
Twisting IL-1 signaling to kill CML stem cells
Comment on
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Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells.Blood. 2016 Dec 8;128(23):2671-2682. doi: 10.1182/blood-2015-11-679928. Epub 2016 Sep 12. Blood. 2016. PMID: 27621307 Free PMC article.
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IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models.Blood. 2016 Dec 8;128(23):2683-2693. doi: 10.1182/blood-2015-11-679985. Epub 2016 Sep 12. Blood. 2016. PMID: 27621309
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