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. 2016 Nov 18;8(2):62-66.
doi: 10.1136/heartasia-2016-010775. eCollection 2016.

Prevalence of atrial fibrillation in the Malaysian communities

Chiao Wen Lim  1 , Sazzli Kasim  1 , Johan Rizwal Ismail  1 , Nicholas Yul Chye Chua  1 , Rizmy Najme Khir  1 , Hafisyatul Aiza Zainal Abidin  1 , Effarezan Abdul Rahman  1 , Mohd Kamal Mohd Arshad  1 , Zubin Ibrahim Othman  1 , Khalid Yusoff  2
Affiliations

Prevalence of atrial fibrillation in the Malaysian communities

Chiao Wen Lim et al. Heart Asia. .

Abstract

Background and aim: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. The REDISCOVER (Responding to Increasing Cardiovascular disease prevalence) study is an observational longitudinal community-based study that tracks changing lifestyles, risk factors and chronic disease in urban and rural areas of Malaysia. In this study, we aim to study the prevalence of AF and its associated risk factors.

Methods: The study was conducted between 2007 and 2014. Participants were required to complete questionnaires on cardiovascular risk factors and medical history, and undergo physical examinations, blood tests, ECG and echocardiography examinations. Demographic variables including weight, height, blood pressure, serum glucose and serum lipid were recorded. Participants with AF were identified from their baseline ECG and at 3-year follow up.

Results: A total of 10 805 subjects participated in the study. Mean age was 52.6(±11.6) years and 56% were female; 4.4% of subjects had a diagnosis of ischaemic heart disease, 1.3% had a previous stroke, 16.7% had diabetes mellitus and 45.6% had hypertension. There were 53 subjects diagnosed with AF at baseline, giving a prevalence of 0.49%, and 0.54% at 3 years. AF was more prevalent in males (58.5% in the AF group compared to 43.9% in sinus rhythm (SR) subjects; p=0.03) and the older age group. Ischaemic heart disease was more prevalent in AF subjects (22.6%) compared to SR subjects (4.4%) (p<0.001). In the AF group previous stroke had occurred in 1.9% of subjects compared to 1.3% in the SR population (p=0.51), and 24.5% of subjects in the AF group had diabetes compared to 16.6% in the SR group (p=0.12). There was a significant difference in the prevalence of hypertension between the AF group (59.6%) compared to the SR subjects (45.5%) (p=0.04).

Conclusions: The prevalence of AF in the Malaysian population was low at 0.54% compared to the global average of 1%. We found that AF was associated with older age, male sex, hypertension, and ischaemic heart disease.

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Conflict of interest statement

Conflicts of Interest: None declared. Participant consent: Obtained.

Figures

Figure 1
Figure 1
REDISCOVER (Responding to Increasing Cardiovascular disease prevalence) site map.
Figure 2
Figure 2
Prevalence of atrial fibrillation according to age group (years).
See this image and copyright information in PMC

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References

    1. Chugh SS, Havmoeller R, Narayanan K et al. . Worldwide epidemiology of atrial fibrillation: a global burden of disease 2010 study. Circulation 2014;129:837–47. doi:10.1161/CIRCULATIONAHA.113.005119 - DOI - PMC - PubMed
    1. Wolf PA, Benjamin EJ, Belanger AJ et al. . Secular trends in the prevalence of atrial fibrillation: the Framingham study. Am Heart J 1996;131:790–5. doi:10.1016/S0002-8703(96)90288-4 - DOI - PubMed
    1. Go AS, Hylek EM, Phillips KA et al. . Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA 2001;285:2370–5. doi:10.1001/jama.285.18.2370 - DOI - PubMed
    1. Davis RC, Hobbs FD, Kenkre JE et al. . Prevalence of atrial fibrillation in the general population and in high-risk groups: The ECHOES study. Europace 2012;14:1553–9. doi:10.1093/europace/eus087 - DOI - PubMed
    1. Stewart S, Hart CL, Hole DJ et al. . Population prevalence, incidence, and predictors of atrial fibrillation in the Renfrew/Paisley study. Heart 2001;86:516–21. doi:10.1136/heart.86.5.516 - DOI - PMC - PubMed

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