Metabolic cues for hematopoietic stem cells

Pia Sommerkamp¹, Andreas Trumpp^{2

3}

Affiliations

¹ Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
² Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. a.trumpp@dkfz.de.
³ Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Comment

Pia Sommerkamp et al. Science. 2016.

. 2016 Dec 2;354(6316):1103-1104.

doi: 10.1126/science.aal3466.

Pia Sommerkamp¹, Andreas Trumpp^{2

3}

¹ Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
² Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. a.trumpp@dkfz.de.
³ Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

No abstract available

Comment on

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.
Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, Suda T, Lin CP, Frenette PS, Ito K. Ito K, et al. Science. 2016 Dec 2;354(6316):1156-1160. doi: 10.1126/science.aaf5530. Epub 2016 Oct 13. Science. 2016. PMID: 27738012 Free PMC article.
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation.
Taya Y, Ota Y, Wilkinson AC, Kanazawa A, Watarai H, Kasai M, Nakauchi H, Yamazaki S. Taya Y, et al. Science. 2016 Dec 2;354(6316):1152-1155. doi: 10.1126/science.aag3145. Epub 2016 Oct 20. Science. 2016. PMID: 27934766