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. 2017 Sep;37(9):1792-1796.
doi: 10.1097/IAE.0000000000001408.

CHANGE OF CHOROIDAL VOLUME IN UNTREATED CENTRAL SEROUS CHORIORETINOPATHY

Laura Pertl  1 , Anton Haas, Silke Hausberger, Tamara Pichler, Dieter F Rabensteiner, Gerald Seidel, Eva M Malle, Martin Weger
Affiliations

CHANGE OF CHOROIDAL VOLUME IN UNTREATED CENTRAL SEROUS CHORIORETINOPATHY

Laura Pertl et al. Retina. 2017 Sep.

Abstract

Purpose: Choroidal hyperpermeability plays a central role in the pathophysiology of central serous chorioretinopathy (CSC). In active CSC undergoing treatment, choroidal thickness decreases if subretinal fluid (SRF) resolves. This study aimed to investigate the change in choroidal thickness and volume in eyes with untreated CSC.

Methods: The authors retrospectively analyzed 27 eyes with treatment-naïve CSC (25 patients), who had a follow-up of 4 to 6 weeks. Retinal and choroidal volume and SRF were segmented manually and calculated using the Spectralis OCT built-in software (Spectralis; Heidelberg Engineering).

Results: In treatment-naïve eyes with CSC, an increase in SRF was significantly associated with an increase in choroidal thickness and volume (rho = 0.93, P < 0.01). Eyes with greater baseline choroidal volume showed a significantly greater decrease in SRF during follow-up (rho = -0.47, P = 0.03).

Conclusion: In this study, an increase in SRF was associated with an increase in both choroidal thickness and volume in eyes with treatment-naïve CSC. Eyes with thicker baseline choroidal volume showed a greater reduction in SRF.

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  • Reply.
    Pertl L, Haas A, Hausberger S, Pichler T, Rabensteiner D, Seidel G, Malle EM, Weger M. Pertl L, et al. Retina. 2018 Jun;38(6):e45. doi: 10.1097/IAE.0000000000002167. Retina. 2018. PMID: 29664822 No abstract available.
  • Correspondence.
    Kumar S, Mayor R, Agarwal M, Singh S, Paul L, Shrivastav A. Kumar S, et al. Retina. 2018 Jun;38(6):e45. doi: 10.1097/IAE.0000000000002166. Retina. 2018. PMID: 29782480 No abstract available.

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