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Case Reports
. 2016 Nov-Dec;26(6):458-460.
doi: 10.4103/0971-4065.177139.

Combined surgical and immunosupressive therapy for encapsulating peritoneal sclerosis

P K Bipi  1 , N Gracious  1 , S Kumar  1 , J George  1
Affiliations
Case Reports

Combined surgical and immunosupressive therapy for encapsulating peritoneal sclerosis

P K Bipi et al. Indian J Nephrol. 2016 Nov-Dec.

Abstract

Encapsulating peritoneal sclerosis (EPS) is an infrequent but serious complication of long-term peritoneal dialysis with 50% mortality and lack consensus on treatment. The pathogenesis of EPS is ill understood, and diagnosis lacks specificity and relies on clinical, radiographic and microscopic evaluation. Since there is no general agreement on managing EPS, we report a case treated successfully with surgery followed by immunosuppressive therapy with tamoxifen and steroids. He later successfully underwent deceased donor renal transplantation.

Keywords: Encapsulating peritoneal sclerosis; peritoneal dialysis; treatment.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Computed tomography abdomen with oral and intravenous contrast revealed prominent bowel loops with thickened peritoneum
Figure 2
Figure 2
Histopathologic examination of peritoneal and omental biopsies revealed adipose tissue cells with large areas of fibrosis, collagenization, inflammatory cells, hemorrhage, and hemosiderin laden macrophages consistent with sclerosing peritonitis
See this image and copyright information in PMC

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