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Review
. 2016 Nov;8(Suppl 10):S795-S798.
doi: 10.21037/jtd.2016.10.107.

Off-pump coronary artery bypass grafting in high-risk patients: a review

Gustavo A Guida  1 , Pierpaolo Chivasso  1 , Daniel Fudulu  1 , Filippo Rapetto  1 , Christo Sedmakov  1 , Roberto Marsico  1 , Mustafa Zakkar  1 , Alan J Bryan  1 , Gianni D Angelini  1
Affiliations
Review

Off-pump coronary artery bypass grafting in high-risk patients: a review

Gustavo A Guida et al. J Thorac Dis. 2016 Nov.

Abstract

The role of off-pump coronary artery bypass (OPCAB) grafting in high risk patients remains controversial. While there have been studies showing the potential benefits of it, there is still a lot to be learned from the application of this technique in this sub-group of patients. The results of the different trials and papers that we reviewed seem to indicate a benefit in the OPCAB group. Despite of the fact that trials were significantly different in methodology, especially when choosing the risk score stratification tool or the cut-off to define high risk the literature seems to suggest a benefit from the use of OPCAB surgery. Here, we present a review which focussed on early and late outcome in high risk patients undergoing on- and off-pump coronary revascularization.

Keywords: CABG; Off-pump coronary artery bypass (OPCAB); coronary by-pass grafting; high risk; off-pump; review.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

References

    1. Cheng DC, Bainbridge D, Martin JE, et al. Does off-pump coronary artery bypass reduce mortality, morbidity, and resource utilization when compared with conventional coronary artery bypass? A meta-analysis of randomized trials. Anesthesiology 2005;102:188-203. 10.1097/00000542-200501000-00028 - DOI - PubMed
    1. Shroyer AL, Grover FL, Hattler B, et al. On-pump versus off-pump coronary-artery bypass surgery. N Engl J Med 2009;361:1827-37. 10.1056/NEJMoa0902905 - DOI - PubMed
    1. Lamy A, Devereaux PJ, Prabhakaran D, et al. Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med 2013;368:1179-88. 10.1056/NEJMoa1301228 - DOI - PubMed
    1. Hlavicka J, Straka Z, Jelinek S, et al. Off-pump versus on-pump coronary artery bypass grafting surgery in high-risk patients: PRAGUE-6 trial at 30 days and 1 year. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2016;160:263-70. 10.5507/bp.2015.059 - DOI - PubMed
    1. Puskas JD, Thourani VH, Kilgo P, et al. Off-pump coronary artery bypass disproportionately benefits high-risk patients. Ann Thorac Surg 2009;88:1142-7. 10.1016/j.athoracsur.2009.04.135 - DOI - PubMed

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